As more researchers turn to whole genome sequencing, the data challenges increase.  A new $1.58 million award from the National Institutes of Health equips Globus Genomics to develop new tools and services that help geneticists overcome these obstacles and unlock new discoveries.


Using the University of Chicago Medicine data warehouse, a team led by CI faculty and fellow Samuel Volchenboum detected a dangerous ripple effect in hospitals: when one patient becomes critically ill, chances of a similar setback increase for others in the same unit.

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How Ancient Himalayan DNA Migrated to Chicago for Analysis


Given its expeditionary namesake, it's only appropriate that Beagle -- the University of Chicago's supercomputer for biomedical research -- works with data from all around the world. But a recent project may qualify as the farthest-traveling data yet, as the HPC resource was used in a new genomic study of populations living in the Himalayan mountain range. 


Beagle is a Cray XE6 supercomputer dedicated to biomedical research, funded by the NIH, owned by the University of Chicago Biological Sciences Division, and operated by the Computation Institute. With 24,000 compute cores, 2 petabytes of storage, and a peak speed of 212 teraflops (212 trillion calculations per second), Beagle allows researchers in biology and medicine to dramatically scale up data analysis, modeling, and simulation tasks.

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The overarching goal of our Center is to identify the genetic and environmental factors that underlie psychiatric disorders, including autism spectrum disorder, schizophrenia, bipolar disorder, depression, anxiety disorders, and child & adolescent psychopathology. Our team develops and applies drastically new mathematical and computational strategies to infer causal relationships among genetic variation, environmental variables and psychiatric phenotypes.


CSGID applies state-of-the-art high-throughput (HTP) structural biology technologies to experimentally characterize the three dimensional atomic structure of targeted proteins from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.

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