News

06
Nov
2017

Two University of Chicago research groups will help build the pilot phase of an ambitious new National Institutes of Health initiative to make U.S. biomedical research data and tools accessible to more scientists.

25
Oct
2017

Like people, bacteria send out signals to attract and repel each other. New research by CI and Argonne scientists determined the molecular structures of a highly specialized set of proteins used by a strain of E. coli bacteria to communicate and defend their turf, a bacterial "social network" that could lead to new strategies for overcoming infectious diseases.

16
Oct
2017

On the World Health Organization’s target list for eradicating disease, hepatitis C is currently among the most wanted. An estimated 71 million people live with the viral liver disease globally, and 1.75 million new infections occur every year. Yet there is reason for optimism, as new treatments, preventative measures, and, perhaps soon, vaccines create novel strategies for driving down infection.

Research

CSGID

CSGID applies state-of-the-art high-throughput (HTP) structural biology technologies to experimentally characterize the three dimensional atomic structure of targeted proteins from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases.

modENCODE project

The goal of the modENCODE project is to provide the biological research community with a comprehensive encyclopedia of genomic functional elements in the model organisms C. elegans and D. melanogaster. modENCODE is run as a Research Network and the consortium is formed by 11 primary projects, divided between worm and fly, spanning the domains of gene structure, mRNA and ncRNA expression profiling, transcription factor binding sites, histone modifications and replacement, chromatin structure, DNA replication initiation and timing, and copy number variation.

SEED logo

With the growing number of available genomes, the need for an environment to support effective comparative analysis increases. The original SEED Project was started in 2003 by the Fellowship for Interpretation of Genomes (FIG) as a largely unfunded open source effort. Argonne National Laboratory and the University of Chicago joined the project, and now much of the activity occurs at those two institutions (as well as the University of Illinois at Urbana-Champaign, Hope college, San Diego State University, the Burnham Institute and a number of other sites).

Researcher Spotlight